Journal of Clinical Medicine, 8 July 2019
Cannabidiol (CBD) is ubiquitous in state-based medical cannabis programs and consumer products for complementary health or recreational use. CBD has intrinsic pharmacologic effects and associated adverse drug events (ADEs) along with the potential for pharmacokinetic and pharm…
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Answers from SCC Members to an inquiry on the safety of using CBD when patients are taking medications metabolized by the P450 system.
Authors: Rafael G. dos Santos, Francisco S. Guimarães, José Alexandre S. Crippa, et al
Expert Opinion on Drug Metabolism & Toxicology, 9 April 2020
Introduction: Recent trials using cannabidiol (CBD) have shown that most acute and prolonged adverse effects of CBD are mild to moderate, with rare serious adverse effects (SAEs). This review focused on analyzing SAEs of CBD and their possible relation to drug-drug interaction…
Authors: Alexandra L. Geffrey, Sarah F. Pollack, Patricia L. Bruno, Elizabeth A. Thiele
Epilepsia, August 2015
OBJECTIVE: Under an expanded access investigational new drug (IND) trial, cannabidiol (CBD) is being studied as a possible adjuvant treatment of refractory epilepsy in children. Of the 25 subjects in the trial, 13 were being treated with clobazam (CLB). Because CLB and CBD are…
Authors: Antonio Waldo Zuardi
Brazilian Journal of Psychiatry, September 2008
OBJECTIVE: The aim of this review is to describe the historical development of research on cannabidiol. METHOD: This review was carried out on reports drawn from Medline, Web of Science and SciELO. DISCUSSION: After the elucidation of the chemical structure of cannabidiol in 1…
Dawn-Marie Steentra, LPN guides us through a day in the life of a Cannabis Nurse. The work requires ongoing compassion, education, and enthusiasm for patient advocacy.
Does cannabis have synergy with other plants? James Brent, DDS reviews the literature.
The IACM conference in Berlin highlighted talks from the top professionals in the field of cannabis science. Christine Milentis, our Executive Secretary, reports on the history of cannabis for medical use and the rights of doctors across the globe to prescribe it.
A study published in BMC Family Practice sought to characterize the clinical practice characteristics of medical professionals who recommend cannabis.
Authors: Marilyn A. Huestis, Renata Solimini, Simona Pichini, Roberta Pacifici, et al
Current Neuropharmacology, 3 June 2019
BACKGROUND: Currently, there is great interest in the potential medical use of cannabidiol (CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD occurred in the 1970s and intensified recently with many discoveries about the endocannabinoid system. M…
Authors: Giulia S. Porcaria, Cary Fub, Emily D. Doll, Emma G. Carter, Robert P. Carson
Epilepsy & Behavior, March 2018
Medically refractory epilepsy continues to be a challenge worldwide, and despite an increasing number of medical therapies, approximately 1 in 3 patients continues to have seizures. Cannabidiol (CBD), one of many constituents of the Cannabis sativa or marijuana plant, has rece…
Authors: Kerstin Iffland, Franjo Grotenhermen
Cannabis and Cannabinoid Research, 1 June 2017
Introduction: This literature survey aims to extend the comprehensive survey performed by Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from updating the literature, this article focuses on clinical studies and CBD potential interactions with o…
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