What would we envision as the best cannabis model for international patient access? This question was explored at a collaborative event in Barcelona just before the COVID-19 lockdowns swept over Spain (and the world).
Joe D. Goldstrich, MD, FACC outlines what we know about the antiviral properties of cannabis and whether or not it could be helpful or detrimental for COVID-19.
Frontiers in Pharmacology, 25 March 2020
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The entourage effect was a proposed explanation for biological observations that endocannabinoid ligand activities can be modified by other lipids released from cells at the same time. An increasing volume of anecdotal reports and interest in the plant have provoked research i…
Annals of Gastroenterology, March-April 2020
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For many centuries, cannabis (marijuana) has been used for both recreational and medicinal purposes. Currently, there are about 192 million cannabis users worldwide, constituting approximately 3.9% of the global population. Cannabis comprises more than 70 aromatic hydrocarbon …
European Journal of Pharmaceutical Sciences, 17 March 2020
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The piperine is an alkaloid naturally found mostly in black pepper with a myriad of pharmacological attributes. The most far reaching indication of piperine is its use as an absorption enhancer, with supportive data regarding piperine’s ability to inhibit first pass effect mec…
Sarah Mann, MD separates myth and conjecture from what is known (and unknown) about cannabis and sex.
Cannabis and Cannabinoid Research, 6 March 2020
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Introduction: Interest in the therapeutic use of cannabidiol (CBD) has reached a fever-pitch in recent months, as CBD-containing products appear everywhere from online retailers to grocery stores and gas stations. The widespread availability of hemp-derived CBD products is con…
Frontiers in Endocrinology, 4 March 2020
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Currently, an increasing number of diseases related to insulin resistance and obesity is an alarming problem worldwide. It is well-known that the above states can lead to the development of type 2 diabetes, hypertension, and cardiovascular diseases. An excessive amount of tria…
CMAJ : Canadian Medical Association journal, 2 March 2020
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Cannabinoid levels can be increased by other medications. Cannabinoids can affect levels of other drugs. Smoking marijuana can increase clearance of some drugs. Additive effects can occur with other drugs. There are potential “red flag” interactions.
Canadian researchers found that the average training from physicians in training was 25% less than what they desired and that further training was paramount for them to engage in cannabis for therapeutic purposes (2020).
CBD appears to have a significant influence on muscle soreness associated with exercise induced muscle damage and delayed onset of muscle soreness when consumed immediately after strenuous exercise.
Journal of Clinical Medicine, 28 February 2020
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Tetrahydrocannabinol (THC) is the primary psychoactive ingredient in cannabis. While the safety of THC and cannabis has been extrapolated from millennia of recreational use, medical marijuana programs have increased exposure among medically complex individuals with comorbid co…