Urogenital Malignancy and Cannabis Use: A Narrative Review

Cannabis is the most commonly used illicit drug worldwide. An increasing number of jurisdictions are legalising cannabis for both medicinal and recreational use. The changing cannabis market has resulted in both an increase in the number of people consuming these compounds, and an increase in the frequency and quantity of cannabis being used. Endogenous and exogenous cannabinoids act on receptors across the entire body including the genitourinary system; however, there is a paucity of understanding of how cannabinoids affect genitourinary malignancy. To present a narrative review of the available literature detailing the relationship between cannabis and the incidence, diagnosis, and management of genitourinary malignancy.

Association between cannabis use with urological cancers: A population-based cohort study and a mendelian randomization study in the UK biobank

Legislation of cannabis use has been approved in many European and North American countries. Its impact on urological cancers is unclear. This study was conducted to explore the association between cannabis use and the risk of urological cancers.

Cannabinoids in Urology. Which Benign Conditions Might They Be Appropriate to Treat: A Systematic Review

Authors: Brian Robert Peter Birch, Charlie Taylor Published in Urology November 2020 Abstract There is growing evidence suggesting cannabinoids may provide suitable alternatives to conventional treatments in an increasing number…

Functional role of cannabinoid receptors in urinary bladder.

Authors: Pradeep Tyagi, Vikas Tyagi, Naoki Yoshimura, Michael Chancellor
Indian Journal of Urology, January-March 2010

Cannabinoids, the active components of Cannabis sativa (maijuana), and their derivatives produce a wide spectrum of central and peripheral effects, some of which may have clinical applications. The discovery of specific cannabinoid receptors and a family of endogenous ligands…

Differential expression of functional cannabinoid receptors in human bladder detrusor and urothelium.

Authors: Vikas Tyagi, Brian J. Philips, Ruthie Su, Marc C. Smaldone, Vickie L. Erickson, et al
The Journal of Urology, April 2009

PURPOSE: Although cannabinoid receptor expression has been demonstrated in human brain and other peripheral neuronal tissues, definitive expression of these receptors in the human bladder has not been reported. Consequently we investigated the expression of functional cannabin…