This category needs to be renamed to be meaningful than “Miscellaneous” but it will do for now. Basically it’s intended for news, research, legal actions and other information about medical marijuana for the general, nonexpert audience: patients, jouralists, the curious, etc.

Systematic review: efficacy and safety of medical marijuana in selected neurologic disorders.

Authors: Barbara S. Koppel, John C.M. Brust, Terry Fife, Jeff Bronstein, Sarah Youssof, et al
Neurology, 29 April 2014

OBJECTIVE: To determine the efficacy of medical marijuana in several neurologic conditions. METHODS: We performed a systematic review of medical marijuana (1948-November 2013) to address treatment of symptoms of multiple sclerosis (MS), epilepsy, and movement disorders. We gra…

Epigenetic control of skin differentiation genes by phytocannabinoids.

Authors: Mariangela Pucci, Cinzia Rapino, Andrea Di Francesco, Enrico Dainese, et al
British Journal of Pharmacology, October 2013

BACKGROUND AND PURPOSE: Endocannabinoid signalling has been shown to have a role in the control of epidermal physiology, whereby anandamide is able to regulate the expression of skin differentiation genes through DNA methylation. Here, we investigated the possible epigenetic r…

Cannabinoid exposure in adolescent female rats induces transgenerational effects on morphine conditioned place preference in male offspring.

Authors: John J Byrnes, Nicole L Johnson, Marian E Schenk, Elizabeth M Byrnes
Journal of Psychopharmacology, October 2012

In the United States, marijuana is one of the drugs most abused by adolescents, with females representing a growing number of users. In previous studies, treatment of adolescent female rats with morphine significantly altered brain reward systems in future offspring. As both c…

Effects of Δ9-tetrahydrocannabinol administration on human encoding and recall memory function: a pharmacological FMRI study.

Authors: Matthijs G. Bossong, Gerry Jager, Hendrika H. van Hell, Lineke Zuurman, et al
Journal of Cognitive Neuroscience, March 2012

Deficits in memory function are an incapacitating aspect of various psychiatric and neurological disorders. Animal studies have recently provided strong evidence for involvement of the endocannabinoid (eCB) system in memory function. Neuropsychological studies in humans have s…

Review on clinical studies with cannabis and cannabinoids 2005-2009.

Based on the clinical results, cannabinoids present an interesting therapeutic potential mainly as analgesics in chronic neuropathic pain, appetite stimulants in debilitating diseases (cancer and AIDS), as well as in the treatment of multiple sclerosis.

Beyond-THC Chemovar Evaluation Survey

The Society of Cannabis Clinicians developed a survey in 2011 that asked about patients’ responses to CBD-rich cannabis.

Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.

Authors: Ethan B. Russo
British Journal of Pharmacology, August 2011

Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic contributions of cannabidiol to cannabis pharmacology and analgesia have been scientifically demonstrated…

SCC Hears McAllister On Cannabis Cancer Research

Researchers have discovered that CBD (Cannabidiol) is a very potent inhibitor of breast cancer metastasis. Doctors who monitor cannabis use by patients were bursting with questions during a talk by Sean McAllister, PhD, who has been studying the anti-cancer effects of cannabinoids in the laboratory.

The CB(2) cannabinoid receptor regulates human sperm cell motility.

Authors: Ekaitz Agirregoitia, Arkaitz Carracedo, Nerea Subirán, Asier Valdivia, et al
Fertility and Sterility, 15 March 2010

OBJECTIVE: To analyze the expression and distribution of cannabinoid receptors in human sperm cells and evaluate the effects of activation of receptors by specific agonists and antagonists, with a special emphasis on the CB(2) receptor. DESIGN: We performed expression assays f…

Cannabis and breastfeeding.

Authors: Aurélia Garry, Virginie Rigourd, Ammar Amirouche, Valérie Fauroux, Sylvie Aubry, Raphaël Serreau
Journal of Toxicology, 2009

Cannabis is a drug derived from hemp plant, Cannabis sativa, used both as a recreational drug or as medicine. It is a widespread illegal substance, generally smoked for its hallucinogenic properties. Little is known about the adverse effects of postnatal cannabis exposure thro…

Interplay between endocannabinoids, steroids and cytokines in the control of human reproduction.

Authors: Natalia Battista, N. Pasquariello, M. Di Tommaso, Mauro Maccarrone
Journal of Neuroendocrinology, May 2008

The use of marijuana, which today is the most used recreational drug, has been demonstrated to affect adversely reproduction. Marijuana smokers, both men and women, show impaired fertility, owing to defective signalling pathways, aberrant hormonal regulation, or wrong timing d…

Non-acute (residual) neurocognitive effects of cannabis use: a meta-analytic study.

Authors: Igor Grant, Raul Gonzalez, Catherine L. Carey, Loki Natarajan, Tanya Wolfson
Journal of the International Neuropsychological Society, July 2003

The possible medicinal use of cannabinoids for chronic diseases emphasizes the need to understand the long-term effects of these compounds on the central nervous system. We provide a quantitative synthesis of empirical research pertaining to the non-acute (residual) effects of…