Neurobiology of cannabinoid receptor signaling

Authors: Beat Lutz, PhD Published in DIALOGUES IN CLINICAL NEUROSCIENCE 2020 Abstract The endocannabinoid system (ECS) is a highly versatile signaling system within the nervous system. Despite its widespread localization, its functions within the context of distinct neural processes are very well discernable and specific. This is remarkable, and the question remains as to how…

Cannabidiol in conjunction with clobazam: analysis of four randomized‐controlled trials

Authors: Boudewijn Gunning, Maria Mazurkiewicz‐Beldzinska, Richard F.M. Chin, Hari Bhathal Charlotte Nortvedt, Eduardo Dunayevich, Daniel Checketts Published in Acta Neurologica Scandinavica September 2020 Abstract Objectives To assess the efficacy and safety profile of add‐on cannabidiol (CBD) in patients with Lennox‐Gastaut syndrome (LGS) and Dravet syndrome (DS) on clobazam and in the overall population of four…

A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report

Authors: Juliana Andrea Ponton, Kim Smyth, Elias Soumbasis, Sergio Andres Llanos, Mark Lewis, Wilhelm August Meerholz & Robert Lawrence Tanguay Published in Journal of Medical Case Reports September 2020 Abstract   Background The pharmacological treatment for autism spectrum disorders is often poorly tolerated and has traditionally targeted associated conditions, with limited benefit for the core…

Understanding Cannabis-Based Therapeutics in Sports Medicine

SCC Member Gretchen E. Maurer, DO, MS and colleagues examine the current research potential for cannabis in sports medicine.

Acute effects of naturalistic THC vs. CBD use on recognition memory: a preliminary study

Authors: Tim Curran , Hélène Devillez , Sophie L. York Williams and L. Cinnamon Bidwell Published in Journal of Cannabis Research  2020 Abstract The ratio of Δ9-tetrahydrocannabinol (THC) to cannabidiol (CBD) varies widely across cannabis strains. CBD has opposite effects to THC on a variety of cognitive functions, including acute THC-induced memory impairments. However, additional…

Most Patients Believe Their Doctors Aren’t a “Good Source” of Information on Cannabis

Survey data reported that less than 20% of patients believe that their primary care providers are knowledgeable about cannabis-specific medical issues.

Perceptions and recommendation behaviors of dermatologists for medical cannabis: A pilot survey

Authors: Samuel Yeroushalmi, Kamaria Nelsona, Andrew Sparks, Adam Friedman Published in Complementary Therapies in Medicine September 2020 Abstract Objectives Evidence suggests that cannabinoids may provide therapeutic benefit to patients with dermatologic conditions. The recommendation behaviors of dermatologists with regards to recommending medical cannabis are unknown. We administered a pilot survey to evaluate dermatologists’ recommendation behaviors…

Medical marijuana certification for patients with sickle cell disease: a report of a single center experience

Authors: Susanna A. Curtis, Dana Lew, Jonathan Spodick, Jeanne E. Hendrickson, Caterina P. Minniti, John D. Roberts Published in Blood Advances August 2020 Abstract More than one-third of adults with sickle cell disease (SCD) report using cannabis-based products. Many states list SCD or pain as qualifying conditions for medical marijuana, but there are few data…

Cannabis use is associated with a lower risk of diabetes in chronic hepatitis C-infected patients (ANRS CO22 Hepather cohort)

Authors: Tangui Barré, Marie Libérée Nishimwe, Camelia Protopopescu, Fabienne Marcellin, Fabrice Carrat, Céline Dorival, Elisabeth Delarocque‐Astagneau, Dominique Larrey, Marc Bourlière, Ventzislava Petrov‐Sanchez, Mélanie Simony, Stanislas Pol, Hélène Fontaine, Patrizia Carrieri on behalf of the ANRS/AFEF Hepather study group Published in Journal of Viral Hepatitis August 2020 Abstract Chronic hepatitis C virus (HCV) infection is a…

A Survey Exploring the Relationship Between Cannabis Use Characteristics and Sexual Function in Men

Authors: Hriday P. Bhambhvani BS, Alex M.Kasman MD, Genester Wilson-King MD, Michael L. Eisenberg MD Published in Sexual Medicine September 2020 Abstract Introduction Cannabis is the most commonly used drug in the United States; however, the effects of cannabis use on male sexual function are poorly understood. Aim To characterize the contemporary landscape of cannabis…

Endometriosis & Cannabis Survey

Get involved in research to understand how women are self-treating for menstrual and endometriosis-related pain using cannabis and other techniques.

Frequent Cannabis Use and Cessation of Injection of Opioids, Vancouver, Canada, 2005-2018

Authors: Hudson Reddon, Kora DeBeck, M Eugenia Socias, Stephanie Lake, Huiru Dong, Mohammad Karamouzian, Kanna Hayashi, Thomas Kerr, M-J Milloy Published in American Journal of Public Health August 2020 Abstract Objectives To evaluate the impact of frequent cannabis use on injection cessation and injection relapse among people who inject drugs (PWID). Methods Three prospective cohorts…