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Pregnancy

Marijuana use during and after pregnancy and association of prenatal use on birth outcomes: A population-based study.

By | Behavioral Health, Mood Disorders, Pediatrics, Pregnancy, Reproduction

Authors: Jean Y. Ko, Van T. Tong, Jennifer M. Bombard, Donald K. Hayes, John Davy, et al
Drug and Alcohol Dependence, June 2018

BACKGROUND: We sought to describe the correlates of marijuana use during and after pregnancy, and to examine the independent relationship between prenatal marijuana use and infant outcomes. STUDY DESIGN: We used state-specific data from the Pregnancy Risk Assessment Monitoring…

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Transfer of Inhaled Cannabis Into Human Breast Milk.

By | Pregnancy, Reproduction

Authors: Teresa Baker, Palika Datta, Kathleen Rewers-Felkins, Heather Thompson, Raja Kallem, Thomas Hale
Obstetrics & Gynecology, May 2018

OBJECTIVE: To evaluate the transfer of delta-9-tetrahydrocannabinol and its metabolites into human breast milk after maternal inhalation of 0.1 g cannabis containing 23.18% delta-9-tetrahydrocannabinol. METHODS:
In this pilot pharmacokinetic study, breast milk samples were col…

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Cannabis use during pregnancy: Pharmacokinetics and effects on child development.

By | Pregnancy, Reproduction

Authors: Kimberly S.Grant, Rebekah Petroff, Nina Isoherranen, Nephi Stella, Thomas M. Burbacher
Pharmacology & Therapeutics, February 2018

The broad-based legalization of cannabis use has created a strong need to understand its impact on human health and behavior. The risks that may be associated with cannabis use, particularly for sensitive subgroups such as pregnant women, are difficult to define because of a p…

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Marijuana and pregnancy: objective education is good, but biased education is not.

By | Pregnancy, Reproduction

Authors: Ciara A. Torres, Carl L. Hart
American Journal of Obstetrics and Gynecology, August 2017

To the Editors: We read with interest the article by Chasnoff, 1 which concluded that physicians should be educated about the negative effects of marijuana use during pregnancy and should discourage its use by pregnant women and women considering becoming pregnant. In our view…

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Maternal Marijuana Use and Adverse Neonatal Outcomes: A Systematic Review and Meta-analysis.

By | Pregnancy, Reproduction

Authors: Shayna Conner, Victoria Bedell, Kim Lipsey, George Macones, Alison Cahill, Methodius Tuuli
Obstetrics & Gynecology, October 2016

OBJECTIVE: To estimate whether marijuana use in pregnancy increases risks for adverse neonatal outcomes and clarify if any increased risk is attributable to marijuana use itself or to confounding factors such as tobacco use. DATA SOURCES: Two authors performed a search of the…

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Marijuana use and its effects in pregnancy.

By | Asthma, Pregnancy, Reproduction, Respiratory Tract Diseases

Authors: Kristin C. Chabarria, Diana A. Racusin, Kathleen M. Antony, Maike Kahr, et al
American Journal of Obstetrics and Gynecology, October 2016

BACKGROUND: It is generally assumed that marijuana is one of the more widely used controlled substances during pregnancy. However, there remains a general paucity of population-based data regarding its use and subsequent perinatal morbidity. We hypothesized that direct patient…

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Prenatal exposure to cannabis and maternal and child health outcomes: a systematic review and meta-analysis

By | Pediatrics, Pregnancy, Reproduction

Authors: J K L Gunn, C B Rosales, K E Center, A Nuñez, S J Gibson, C Christ, J E Ehiri
BMJ Open, 5 April 2016

Objective: To assess the effects of use of cannabis during pregnancy on maternal and fetal outcomes. Data sources: 7 electronic databases were searched from inception to 1 April 2014. Studies that investigated the effects of use of cannabis during pregnancy on maternal and fet…

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The psychoactive compound of Cannabis sativa, Δ(9)-tetrahydrocannabinol (THC) inhibits the human trophoblast cell turnover.

By | Pregnancy, Reproduction

Authors: M.A. Costa, B.M. Fonseca, F. Marques, N.A. Teixeira, G. Correia-da-Silva
Toxicology, 6 August 2015

The noxious effects of cannabis consumption for fertility and pregnancy outcome are recognized for years. Its consumption during gestation is associated with alterations in foetal growth, low birth weight and preterm labor. The main psychoactive molecule of cannabis, Δ(9)-tetr…

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Prenatal cannabis exposure and infant outcomes: overview of studies.

By | Pediatrics, Pregnancy, Reproduction

Authors: A.C. Huizink
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 3 July 2014

Accumulating evidence from both human and preclinical studies indicates maternal substance use during pregnancy can affect fetal development, birth weight and infant outcomes. Thus, the prenatal period can be regarded as an important and potentially sensitive period of develop…

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Cannabis, the pregnant woman and her child: weeding out the myths.

By | Pregnancy

Authors: S C Jaques, A Kingsbury, P Henshcke, C Chomchai, S Clews, J Falconer, M E Abdel-Latif, et al
Journal of Perinatology, June 2014

To review and summarise the literature reporting on cannabis use within western communities with specific reference to patterns of use, the pharmacology of its major psychoactive compounds, including placental and fetal transfer, and the impact of maternal cannabis use on preg…

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