Maternal Marijuana Use and Adverse Neonatal Outcomes: A Systematic Review and Meta-analysis.

Authors: Shayna Conner, Victoria Bedell, Kim Lipsey, George Macones, Alison Cahill, Methodius Tuuli
Obstetrics & Gynecology, October 2016

OBJECTIVE: To estimate whether marijuana use in pregnancy increases risks for adverse neonatal outcomes and clarify if any increased risk is attributable to marijuana use itself or to confounding factors such as tobacco use. DATA SOURCES: Two authors performed a search of the…

Marijuana use and its effects in pregnancy.

Authors: Kristin C. Chabarria, Diana A. Racusin, Kathleen M. Antony, Maike Kahr, et al
American Journal of Obstetrics and Gynecology, October 2016

BACKGROUND: It is generally assumed that marijuana is one of the more widely used controlled substances during pregnancy. However, there remains a general paucity of population-based data regarding its use and subsequent perinatal morbidity. We hypothesized that direct patient…

Prenatal exposure to cannabis and maternal and child health outcomes: a systematic review and meta-analysis

Authors: J K L Gunn, C B Rosales, K E Center, A Nuñez, S J Gibson, C Christ, J E Ehiri
BMJ Open, 5 April 2016

Objective: To assess the effects of use of cannabis during pregnancy on maternal and fetal outcomes. Data sources: 7 electronic databases were searched from inception to 1 April 2014. Studies that investigated the effects of use of cannabis during pregnancy on maternal and fet…

The psychoactive compound of Cannabis sativa, Δ(9)-tetrahydrocannabinol (THC) inhibits the human trophoblast cell turnover.

Authors: M.A. Costa, B.M. Fonseca, F. Marques, N.A. Teixeira, G. Correia-da-Silva
Toxicology, 6 August 2015

The noxious effects of cannabis consumption for fertility and pregnancy outcome are recognized for years. Its consumption during gestation is associated with alterations in foetal growth, low birth weight and preterm labor. The main psychoactive molecule of cannabis, Δ(9)-tetr…

Prenatal cannabis exposure and infant outcomes: overview of studies.

Authors: A.C. Huizink
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 3 July 2014

Accumulating evidence from both human and preclinical studies indicates maternal substance use during pregnancy can affect fetal development, birth weight and infant outcomes. Thus, the prenatal period can be regarded as an important and potentially sensitive period of develop…

Cannabis, the pregnant woman and her child: weeding out the myths.

Authors: S C Jaques, A Kingsbury, P Henshcke, C Chomchai, S Clews, J Falconer, M E Abdel-Latif, et al
Journal of Perinatology, June 2014

To review and summarise the literature reporting on cannabis use within western communities with specific reference to patterns of use, the pharmacology of its major psychoactive compounds, including placental and fetal transfer, and the impact of maternal cannabis use on preg…

Association between pre- and perinatal exposures and Tourette syndrome or chronic tic disorder in the ALSPAC cohort.

Authors: Carol A. Mathews, Jeremiah M. Scharf, Laura L. Miller, Corrie Macdonald-Wallis, et al
British Journal of Psychiatry, January 2014

BACKGROUND: Tourette syndrome and chronic tic disorder are heritable but aetiologically complex. Although environment plays a role in their development, existing studies of non-genetic risk factors are inconsistent. AIMS:
To examine the association between pre- and perinatal e…

Pregnancy, breast-feeding, and marijuana: a review article.

Authors: Meg Hill, Kathryn Reed
Obstetrical & Gynecological Survey, October 2013

Marijuana is a commonly used drug. At present, it remains an illegal substance in most areas of the United States. Recent controversy regarding the perceived harms of this drug has resulted in debate in both legal and medical circles. This review examines evidence regarding th…

Prenatal substance abuse: short- and long-term effects on the exposed fetus.

Authors: Marylou Behnke, Vincent C. Smith, COMMITTEE ON SUBSTANCE ABUSE, COMMITTEE ON FETUS AND NEWBORN
Pediatrics, March 2013

Prenatal substance abuse continues to be a significant problem in this country and poses important health risks for the developing fetus. The primary care pediatrician’s role in addressing prenatal substance exposure includes prevention, identification of exposure, recognition…

Birth outcomes associated with cannabis use before and during pregnancy.

Authors: Mohammad R. Hayatbakhsh, Vicki J. Flenady, Kristen S. Gibbons, Ann M. Kingsbury, et al
Pediatric Research, February 2012

INTRODUCTION: This study aimed to examine the association between cannabis use before and during pregnancy and birth outcomes. RESULTS: Overall, 26.3% of women reported previous use of cannabis and 2.6% reported current use. Multivariate analysis, controlling for potential con…

School achievement in 14-year-old youths prenatally exposed to marijuana.

Authors: Lidush Goldschmidt, Gale A. Richardson, Jennifer A. Willford, Stevan G. Severtson, Nancy L. Day
Neurotoxicology and Teratology, January-February 2012

The relation between prenatal marijuana exposure (PME) and school achievement was evaluated in a sample of 524 14-year-olds. Women were recruited during pregnancy and assessed, along with their offspring, at multiple phases from infancy to early adulthood. The sample represent…

Cannabis Treatments in Obstetrics and Gynecology: A Historical Review.

Authors: Ethan Russo
Journal of Cannabis Therapeutics, October 2008

Cannabis has an ancient tradition of usage as a medicine in obstetrics and gynecology. This study presents that history in the literature to the present era, compares it to current ethnobotanical, clinical and epidemiological reports, and examines it in light of modern develop…