Miranda-Massaria, Jorge; Santiago, Christian; Vega Mena, Carlos; Dun, Matthew; Gonzalez, Michael; Claudio, Jaime; Olalde, Jose; Silva-Morales, José; Bloom, Joseph; Colón-Sáez, José; Soler Jorge


May 25,  2023


The current standard-of-care treatment regimens for cancer frequently have serious and irreversible adverse effects. Ideally, therapeutic modalities should help control symptoms and improve the patient’s quality of life while causing minimal or no toxic effects. In this regard, it is worth examining cannabidiol (CBD) for its potential anticancer properties. CBD may possess antitumor activity through several mechanisms, including regulating reactive oxygen species, endoplasmic reticulum stress, inflammation, and immune modulation. In addition, pre-clinical studies indicate that CBD is a potential modulator of growth factors and induces apoptosis in tumor cells. This review summarizes the evidence regarding the effects of CBD as a non-toxic adjuvant in cancer care.

Cancer is one of the leading causes of death worldwide and the first or second leading cause in people younger than 70 in 112 countries.1 Lifestyle habits associated with increased cancer risk, such as tobacco, obesity, low physical activity, alcohol, processed food, and other dietary/nutritional issues, have become more prevalent and may have led to an increased incidence of this condition…..

DOI: 10.14200/jrm.2023.0002


Miranda-Massaria, J., Santiago, C., Vega Mena, C., Dun, M., Gonzalez, M., Claudio, J., … & Jorge, S. (2023). CBD as a Physiological Modulator for Cancer. Journal of Restorative Medicine, 13(1)..