Kah Ling Liew, Ermanno Capuano and Bernard Yung

Published in BMJ Case Reports CP

October 2021



Conventional lung cancer treatments include surgery, chemotherapy and radiotherapy; however, these treatments are often poorly tolerated by patients. Cannabinoids have been studied for use as a primary cancer treatment. Cannabinoids, which are chemically similar to our own body’s endocannabinoids, can interact with signalling pathways to control the fate of cells, including cancer cells. We present a patient who declined conventional lung cancer treatment. Without the knowledge of her clinicians, she chose to self-administer ‘cannabidiol (CBD) oil’ orally 2–3 times daily. Serial imaging shows that her cancer reduced in size progressively from 41 mm to 10 mm over a period of 2.5 years. Previous studies have failed to agree on the usefulness of cannabinoids as a cancer treatment. This case appears to demonstrate a possible benefit of ‘CBD oil’ intake that may have resulted in the observed tumour regression. The use of cannabinoids as a potential cancer treatment justifies further research.


DOI: 10.1136/bcr-2021-244195


Liew, K. L., Capuano, E., & Yung, B. (2021). Lung cancer patient who had declined conventional cancer treatment: could the self-administration of ‘CBD oil’be contributing to the observed tumour regression?. BMJ Case Reports CP, 14(10), e244195.