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Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs.

By | General Information, Veterinary Medicine

Authors: Lisa R. Bartner, Stephanie McGrath, Sangeeta Rao, Linda K. Hyatt, Luke A. Wittenburg
Canadian Journal of Veterinary Research, July 2018

The purpose of this study was to determine the pharmacokinetics of cannabidiol (CBD) in healthy dogs. Thirty, healthy research dogs were assigned to receive 1 of 3 formulations (oral microencapsulated oil beads, oral CBD-infused oil, or CBD-infused transdermal cream), at a dos…

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Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs.

By | General Information, Veterinary Medicine

Authors: Lauri-Jo Gamble1, Jordyn M. Boesch, Christopher W. Frye, Wayne S. Schwark, Sabine Mann, Lisa Wolfe, Holly Brown, Erin S. Berthelsen, Joseph J. Wakshlag
Frontiers in Veterinary Science, July 2018

Objectives: The objectives of this study were to determine basic oral pharmacokinetics, and assess safety and analgesic efficacy of a cannabidiol (CBD) based oil in dogs with osteoarthritis (OA). Methods: Single-dose pharmacokinetics was performed using two different doses of…

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The influence of THC:CBD oromucosal spray on driving ability in patients with multiple sclerosis-related spasticity.

By | Driving, Immune System Diseases , Multiple Sclerosis, Muscle Spasticity, Muscular Diseases

Authors: Elisabeth G. Celius, Carlos Vila
Brain and Behavior, 6 April 2018

BACKGROUND: Driving ability is a key function for the majority of patients with multiple sclerosis (MS) to help maintain daily interactions. Both physical and cognitive disability, as well as treatments, may affect the ability to drive. Spasticity is a common symptom associate…

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Our Letter to the Editor of JAMA

By | News

SCC Board Members recently published a Letter to the Editor of JAMA opposing several key provisions in the “model guidelines” the Federation wants the state medical boards to adopt. Read More….

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Characterization of endocannabinoids and related acylethanolamides in the synovial fluid of dogs with osteoarthritis: a pilot study.

By | Veterinary Medicine

Authors: Carmela Valastro, Debora Campanile, Mariarosaria Marinaro, Delia Franchini, Fabiana Piscitelli, Roberta Verde, Vincenzo Di Marzo, Antonio Di Bello
BMC Veterinary Research, 6 November 2017

BACKGROUND: Cannabis-based drugs have been shown to be effective in inflammatory diseases. A number of endocannabinoids including N- arachidonoylethanolamide (anandamide, AEA) and 2-arachidonyl glycerol (2-AG) with activity at the cannabinoid receptors (CBR) CBR1 and CBR2, hav…

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Physicians-in-training are not prepared to prescribe medical marijuana.

By | Medical Cannabis

Authors: Anastasia B. Evanoff, Tiffany Quan, Carolyn Dufault, Michael Awad, Laura Jean Bierut
Drug and Alcohol Dependence, 1 November 2017

BACKGROUND: While medical marijuana use is legal in more than half of U.S. states, evidence is limited about the preparation of physicians-in-training to prescribe medical marijuana. We asked whether current medical school and graduate medical educational training prepare phys…

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Spatial distribution of cannabinoid receptor type 1 (CB1) in normal canine central and peripheral nervous system.

By | General Information, Veterinary Medicine

Authors: Jessica Freundt-Revilla, Kristel Kegler, Wolfgang Baumgärtner, Andrea Tipold
PLoS One, 10 July 2017

The endocannabinoid system is a regulatory pathway consisting of two main types of cannabinoid receptors (CB1 and CB2) and their endogenous ligands, the endocannabinoids. The CB1 receptor is highly expressed in the central and peripheral nervous systems (PNS) in mammalians and…

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An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies.

By | Veterinary Medicine

Authors: Kerstin Iffland, Franjo Grotenhermen
Cannabis and Cannabinoid Research, 1 June 2017

Introduction: This literature survey aims to extend the comprehensive survey performed by Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from updating the literature, this article focuses on clinical studies and CBD potential interactions with o…

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The use of cannabinoids in animals and therapeutic implications for veterinary medicine: a review.

By | Veterinary Medicine

Authors: Leos Landa, Alexandra Sulcova, P. Gbelec
Veterinarni Medicina, March 2016

Cannabinoids/medical marijuana and their possible therapeutic use have received increased attention in human medicine during the last years. This increased attention is also an issue for veterinarians because particularly companion animal owners now show an increased interest…

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