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Preliminary Assessment of Medical Cannabis Consumption by Cancer Survivors

This study indicates that cancer survivors may indeed consume cannabis for symptom relief, and not merely for recreational purposes. More research is needed to study the adequate role that cannabis may have for treating symptoms associated with cancer survivorship.

Medical marijuana certification for patients with sickle cell disease: a report of a single center experience

Authors: Susanna A. Curtis, Dana Lew, Jonathan Spodick, Jeanne E. Hendrickson, Caterina P. Minniti, John D. Roberts Published in Blood Advances August 2020 Abstract More than one-third of adults with sickle cell disease (SCD) report using cannabis-based products. Many states list SCD or pain as qualifying conditions for medical marijuana, but there are few data…

Alleviative effects of Cannabis flower on migraine and headache

Author: Sarah S. Stitha, Jegason P.Diviant, Franco Brockelman, KeenanKeeling, BrandenHall, Storri Lucern, Jacob M.Vigil, Kathleen MacMillan MacMillan, Amanda Keddy, James Furlon Published in Science Direct July 2020 Abstract Objective: Few studies to date have measured the real-time effects of consumption of common and commercially available Cannabis products for the treatment of headache and migraine under naturalistic…

The Therapeutic Potential and Usage Patterns of Cannabinoids in People with Spinal Cord.

Authors: Kylie J. Nabata, Emmanuel K. Tse, Tom E. Nightingale, Amanda H.X. Lee, Janice J., et al
Current Neuropharmacology, 19 April 2020

BACKGROUND: People with spinal cord injuries (SCI) commonly experience pain and spasticity, but limitations of current treatments have generated interest in cannabis as a possible therapy. OBJECTIVES: We conducted this systematic review to: 1) examine usage patterns and reason…

Adding medical cannabis to standard analgesic treatment for fibromyalgia: a prospective observational study.

Authors: Valeria Giorgi, Sara Bongiovanni, Fabiola Atzeni, Daniela Marotto, et al
Clinical and experimental rheumatology, January-February 2020

OBJECTIVES: To assess any clinical improvement attributable to the addition of medical cannabis treatment (MCT) to the stable (>3 months) standard analgesic treatment of fibromyalgia (FM) patients, the retention rate and any changes in the concomitant analgesic treatment over …

Use of cannabinoids in cancer patients: A Society of Gynecologic Oncology (SGO) clinical practice statement.

Authors: B. Whitcomb, C. Lutman, M. Pearl, E. Medlin, E. Prendergast, K. Robison, W. Burke
Gynecologic Oncology, 10 January 2020

Tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN) affect the human endocannabinoid system. Cannabinoids reduce chemotherapy induced nausea or vomiting (CINV) and neuropathic pain. Each state has its own regulations for medical and recreational cannabis use. Ef…

The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities.

Authors: Dixon H. Xu, Benjamin D. Cullen, Meng Tang, Yujiang Fang
Current Pharmaceutical Biotechnology, December 2019

BACKGROUND: Peripheral neuropathy can significantly impact the quality of life for those who are affected, as therapies from the current treatment algorithm often fail to deliver adequate symptom relief. There has, however, been an increasing body of evidence for the use of ca…

The Potential Benefits of Palmitoylethanolamide in Palliation: A Qualitative Systematic Review.

Authors: Mellar P. Davis, Bertrand Behm, Zankhana Mehta, Carlos Fernandez
American Journal of Hospice and Palliative Medicine, December 2019

Palmitoylethanolamide (PEA) is a nutraceutical endocannabinoid that was retrospectively discovered in egg yolks. Feeding poor children with known streptococcal infections prevented rheumatic fever. Subsequently, it was found to alter the course of influenza. Unfortunately, the…

The Role of the Endocannabinoid System in Aetiopathogenesis of Endometriosis: A Potential Therapeutic Target

Authors: Keisuke Tanaka, Leah Mayne, Akram Khalil, David Baartz, Lars Eriksson, Sally-Anne Mortlock, et al
European Journal of Obstetrics & Gynecology and Reproductive Biology, 15 November 2019

Endometriosis affects a large proportion of women during their reproductive years and is associated with pain and infertility, also affecting psychological wellbeing and quality of life. The pathogenesis of the disease remains unclear, although it is believed to be multifactor…

The effectiveness of self-directed medical cannabis treatment for pain.

Authors: Xiaoxue Li, Jacob M.Vigil, Sarah S. Stith, Franco Brockelman, Keenan Keeling, Branden Hall
Complementary Therapies in Medicine, October 2019

The prior medical literature offers little guidance as to how pain relief and side effect manifestation may vary across commonly used and commercially available cannabis product types. We used the largest dataset in the United States of real-time responses to and side effect r…

Cannabis and Pain.

Authors: Ethan B. Russo
Pain Medicine, 16 September 2019

This editorial is occasioned by the publication in Pain Medicine of two quite distinct articles [1,2] on the topical subject of cannabis and pain. As a point of departure, it is necessary to define terms. Cannabis sativa L. is a highly variable biochemical and morphological pl…

Safety and Efficacy of Medical Cannabis in Fibromyalgia.

Authors: Iftach Sagy, Lihi Bar-Lev Schleider, Mahmoud Abu-Shakra, Victor Novack
Journal of Clinical Medicine, 5 June 2019

BACKGROUND: Chronic pain may be treated by medical cannabis. Yet, there is scarce evidence to support the role of medical cannabis in the treatment of fibromyalgia. The aim of the study was to investigate the characteristics, safety, and effectiveness of medical cannabis thera…