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Acute effects of naturalistic THC vs. CBD use on recognition memory: a preliminary study

Authors: Tim Curran , Hélène Devillez , Sophie L. York Williams and L. Cinnamon Bidwell Published in Journal of Cannabis Research  2020 Abstract The ratio of Δ9-tetrahydrocannabinol (THC) to cannabidiol (CBD) varies widely across cannabis strains. CBD has opposite effects to THC on a variety of cognitive functions, including acute THC-induced memory impairments. However, additional…

The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD).

Post-traumatic stress disorder (PTSD) is a psychiatric disorder of significant prevalence and morbidity, whose pathogenesis relies on paradoxical changes of emotional memory processing. An ideal treatment would be a drug able to block the pathological over-consolidation and continuous retrieval of the traumatic event, while enhancing its extinction and reducing the anxiety symptoms.

The endocannabinoid system in normal and pathological brain ageing.

Authors: Andras Bilkei-Gorzo
Philosophical Transactions of the Royal Society B: Biological Sciences, 5 December 2012

The role of endocannabinoids as inhibitory retrograde transmitters is now widely known and intensively studied. However, endocannabinoids also influence neuronal activity by exerting neuroprotective effects and regulating glial responses. This review centres around this less-s…