The Role of Cannabinoids in Prostate Cancer

By | Cancer, CBD, Research Articles, THC

The Role of Cannabinoids in Prostate Cancer

From the Indian Journal of Urology in 2012 comes this information regarding cannabis and prostate cancer: ‘It is our conclusion that it would be of interest to conduct clinical trials involving medicinal cannabis or other cannabinoid agonists, comparing clinical markers such as PSA with controls, especially in men with bone metastatic prostate cancer, whom would not only benefit from the possible anti-androgenic effects of cannabinoids but also from analgesia of bone pain, improving quality of life, while reducing narcotic consumption and preventing opioid dependence.’ Read More

Cannabinoids Reduce ErbB2-driven Breast Cancer Progression

By | Cancer, Endocannabinoid System, Research Articles

Cannabinoids in ErbB2 Breast Cancer | Cannabis Breast Cancer

ErbB2-overexpressing breast tumors are characterized by very aggressive clinical courses and decreased survival rates, mostly due to the poorly differentiated, highly proliferative and highly invasive nature of their constituent cells. From Italy comes this research, published in Molecular Cancer in 2010, sharing findings which suggest that these highly aggressive and low responsive tumors could be efficiently treated with non-psychoactive CB2-selective agonists without affecting the surrounding healthy tissue. Read More

CBD Controls Breast Cancer Aggressiveness

By | Cancer, CBD, Research Articles

CBD Controls Breast Cancer AggressivenessPublished in September 2011 in the journal Breast Cancer Research and Treatment, Sean McAllister et all described CBD interacting through a cellular system that regulates the expression of key transcriptional factors (e.g., Id-1) that control breast cancer cell proliferation, migration, and invasion. Read More

Cannabinoids Inhibit Pancreatic Cancer Cells

By | Cancer, Research Articles

Cannabinoids Inhibit Pancreatic Cancer Cells

From the June, 2013 issue of Cell Death and Disease comes news about cannabinoids and pancreatic cancer. The article is scientifically dense, but the results demonstrated for the first time that cannabinoid-dependent autophagy induction in pancreatic adenocarcinoma cells is strictly related to the inhibition of energetic metabolism. Welcome news about an otherwise grim disease. Read More

Cannabidiol As A Novel Inhibitor Of Id-1 Gene Expression In Aggressive Breast Cancer Cells

By | Cancer, CBD, Research Articles

CBD Inhibits Metastatic Breast Cancer Cell Gene Expression

CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic breast cancer cells leading to the down-regulation of tumor aggressiveness. In 2007, at the California Pacific Medical Center Research Institute, a study was published by Sean McAllister in the journal Molecular Cancer Therapeutics titled: Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. Read More