The emerging role of the endocannabinoid system in cardiovascular disease.

Authors: Pál Pacher, Sabine Steffens
Seminars in Immunopathology, June 2009

Endocannabinoids are endogenous bioactive lipid mediators present both in the brain and various peripheral tissues, which exert their biological effects via interaction with specific G-protein-coupled cannabinoid receptors, the CB(1) and CB(2). Pathological overactivation of t…