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Lower levels of cannabinoid 1 receptor mRNA in female eating disorder patients: association with wrist cutting as impulsive self-injurious behavior.

Authors: Marc Schroeder, Christian Eberlein, Martina de Zwaan, Johannes Kornhuber, Stefan Bleich, Helge Frieling
Psychoneuroendocrinology, December 2012

The cannabinoid 1 (CB 1) receptor as the primary mediator of the endocannabinoid (EC) system was found to play a role in eating disorders (EDs), depression, anxiety, and suicidal behavior. The CB 1 receptor is assumed to play a crucial role in the central reward circuitry with…