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Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice.

Authors: Hai-Ying Zhang, Ming Gao, Qing-Rong Liu, Guo-Hua Bi, Xia Li, Hong-Ju Yang, et al
Proceedings of the National Academy of Sciences, 18 November 2014

Cannabinoid CB2 receptors (CB2Rs) have been recently reported to modulate brain dopamine (DA)-related behaviors; however, the cellular mechanisms underlying these actions are unclear. Here we report that CB2Rs are expressed in ventral tegmental area (VTA) DA neurons and functi…