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Masturbation to Orgasm Stimulates the Release of the Endocannabinoid 2-Arachidonoylglycerol in Humans.

Authors: Johannes Fuss, Laura Bindila, Klaus Wiedemann, Matthias K. Auer, Peer Briken, Sarah V. Biedermann
Journal of Sexual Medicine, November 2017

BACKGROUND: Endocannabinoids are critical for rewarding behaviors such as eating, physical exercise, and social interaction. The role of endocannabinoids in mammalian sexual behavior has been suggested because of the influence of cannabinoid receptor agonists and antagonists o…