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Cannabis: From a Plant That Modulates Feeding Behaviors toward Developing Selective Inhibitors of the Peripheral Endocannabinoid System for the Treatment of Obesity and Metabolic Syndrome.

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Authors: Shira Hirsch, Joseph Tam
Toxins, 15 May 2019
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In this review, we discuss the role of the endocannabinoid (eCB) system in regulating energy and metabolic homeostasis. Endocannabinoids, via activating the cannabinoid type-1 receptor (CB1R), are commonly known as mediators of the thrifty phenotype hypothesis due to their act…

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The impact of marijuana use on glucose, insulin, and insulin resistance among US adults.

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Authors: Elizabeth A. Penner, Hannah Buettner, Murray A. Mittleman
The American Journal of Medicine, July 2013
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BACKGROUND: There are limited data regarding the relationship between cannabinoids and metabolic processes. Epidemiologic studies have found lower prevalence rates of obesity and diabetes mellitus in marijuana users compared with people who have never used marijuana, suggestin…

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