Case Reports

SCC supports the practice of evidence-based cannabinoid medicine. This collection of research studies exists to guide clinical decision making. All included articles have been vetted by Board members to ensure that only rigorous, unbiased, and non-commercialized studies are included.


Entry ID8

Medical ConditionAdverse effects


Achalasia, status post myotomy
Medical Condition
Adverse effects
Postprandial cramps, frequent nausea, general dyspepsia
About 2 years post lower esophageal sphincterotomy for achalasia, this 35-year-old female suffered from general dyspepsia associated with difficulty falling asleep. She used both inhaled and ingested marijuana daily in small amounts which relieved her symptoms without the need of additional medications.
Patient information
Brief history and target symptomatology
35-year-old female social worker, married, two teenagers at home, employed full-time. Underwent Heller myotomy for achalasia. Esophagram six weeks postop showed good distensibility of the esophagus, and quick emptying. Postprandial cramps and frequent nausea started in the postoperative period and continue 15 months postop.
Previous and current conventional therapies
The patient was treated with Protonix and Pepcid following Heller myotomy. She no longer takes those medicines and uses cannabis instead.
Clinical response to Cannabis
Relief of GI discomfort and of associated sleep disorder.
Additional Comments
According to NORML ( Main » Library » Health Reports » Recent Research on Medical Marijuana » Gastrointestinal Disorders): "Preclinical studies demonstrate that activation of the CB1 and CB2 cannabinoid receptors exert biological functions on the gastrointestinal tract.[6] Effects of their activation in animals include suppression of gastrointestinal motility,[7] inhibition of intestinal secretion,[8] reduced acid reflux,[9] and protection from inflammation,[10] as well as the promotion of epithelial wound healing in human tissue.[
Usual method of Cannabis administration
Frequency of Usage: Time Per Day
Frequency of Usage: Days per Week