Case Reports

SCC supports the practice of evidence-based cannabinoid medicine. This collection of research studies exists to guide clinical decision making. All included articles have been vetted by Board members to ensure that only rigorous, unbiased, and non-commercialized studies are included.


Entry ID17

Medical ConditionAdverse effects


Marijuana Is Helpful in Xerostomia
Medical Condition
Cancer chemotherapy
A 39-year-old retired cab driver treated with radiation and chemotherapy for tonsillar cancer 4 years ago finds medical marijuana helpful in reducing oral mucosal dryness and the need for special dental hygiene.
Patient information
Brief history and target symptomatology
The patient drove a cab for 39 years and retired 2 years ago. He has suffered from psoriasis for 16 years and currently takes IV Orencia w. maltose ( generic: Abatacept) for severe hand pain due to psoriatic arthritis. He was a longtime tobacco smoker until 2010 when he was diagnosed with right tonsillar cancer and treated with radiation and long-term chemotherapy. He now suffers from dry mouth and decreased appetite. He spends a long time flossing and brushing his teeth after every meal to decrease his risk of dental caries. He does not suffer from xerostomia and does not have Sjogren's syndrome to his knowledge.
Previous and current conventional therapies
Cough lozenges were not effective.
Clinical response to Cannabis
Marijuana subjectively decreases the unpleasant feeling of dry mouth and subjectively increases his production of saliva. It also "definitely" improves his appetite.
Additional Comments
Alterations in whole saliva flow rate induced by fractionated radiotherapy
WB Wescott, JG Mira, EN Starcke, IL Shannon and JI Thornby
American Journal of Roentgenology. 1978;130: 145-149.

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Usual method of Cannabis administration
Frequency of Usage: Time Per Day
Frequency of Usage: Days per Week