Targeting the Endocannabinoid System in Psychiatric Illness.

Prevalence of psychiatric disorders continues to rise globally, yet remission rates and patient outcome remain less than ideal. As a result, novel treatment approaches for these disorders are necessary to decrease societal economic burden, as well as increase individual functi…

Women’s perspectives about cannabis use during pregnancy and the postpartum period: An integrative review.

Authors: Hamideh Bayrampour, Mike Zahradnik, Sarka Lisonkova, Patti Janssen
Preventive Medicine, February 2019

Cannabis is the most commonly used illicit drug among general and pregnant populations. Despite recommendations to abstain from cannabis use, its use is increasing during the perinatal period. In this integrative review, we aim to understand women’s perspectives about the heal…

The endocannabinoid system and stroke: A focused review.

Authors: Bradley Kolb, Hamidreza Saber, Hassan Fadel, Gary Rajah
Brain Circulation, January-March 2019

Stroke is an important cause of morbidity and mortality worldwide. Development of novel neuroprotectants is of paramount importance. This review seeks to summarize the recent evidence for the role of the endocannabinoid signaling system in stroke pathophysiology, as well as th…

Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer.

Authors: Golnaz Sharafi, Hong He, Mehrdad Nikfarjam
Journal of Pancreatic Cancer, 25 January 2019

Background: Cannabinoid extracts may have anticancer properties, which can improve cancer treatment outcomes. The aim of this review is to determine the potentially utility of cannabinoids in the treatment of pancreatic cancer. Methods: A literature review focused on the biolo…

Therapeutic potential of cannabinoids as neuroprotective agents for damaged cells conducing to movement disorders.

Authors: Mario Antonazzo, María Botta, Harkaitz Bengoetxea, José Ángel Ruiz-Ortega, Teresa Morera-Herreras
International Review of Neurobiology, 2019

The basal ganglia (BG), an organized network of nuclei that integrates cortical information, play a crucial role in controlling motor function. In fact, movement disorders such as Parkinson’s disease (PD) and Huntington’s disease (HD) are caused by the degeneration of specific…

A hunger for hunger: a review of palliative therapies for cancer-associated anorexia.

Authors: Daniel S. Childs, Aminah Jatoi
Annals of Palliative Medicine, January 2019

Cancer-associated anorexia, or loss of appetite, is prevalent, distressing to patients and their families, and associated with poorer outcomes in patients with advanced cancer. A well-defined therapeutic strategy remains to be defined. We present here a review of appetite loss…