Preferential epithelial expression of type-1 cannabinoid receptor (CB1R) in the developing canine embryo.

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Authors: Andrea Pirone, Carla Lenzi, Alessandra Coli, Elisabetta Giannessi, Maria Rita Stornelli, Vincenzo Miragliotta
SpringerPlus, 22 December 2015
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The use of cannabinoid receptor agonists is gaining a strong interest both in human and veterinary medicine. The potential use of cannabimimetic compounds in companion animals was reviewed in 2007 for their role in tissue inflammation and pain. A better knowledge of type-1 can…

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Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.

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Authors: Dacai Xu, Jianglin Wang, Zhenkang Zhou, Zhiwei He, Qing Zhao
Molecular Medicine Reports, December 2015
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Hepatocellular carcinoma (HCC) is the leading cause of cancer-associated mortality worldwide; however, only limited therapeutic treatments are currently available. The present study aimed to investigate the effects of cannabinoids as novel therapeutic targets in HCC. In additi…

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