Role of Endocannabinoid Activation of Peripheral CB1 Receptors in the Regulation of Autoimmune Disease.

Authors: Jessica Margaret Sido, Prakash S. Nagarkatti, Mitzi Nagarkatti
International Reviews of Immunology, 2015

The impact of the endogenous cannabinoids (AEA, 2-AG, PEA, and virodamine) on the immune cell expressed cannabinoid receptors (CB1, CB2, TRPV-1, and GPR55) and consequent regulation of immune function is an exciting area of research with potential implications in the preventio…

Overcoming the Bell-Shaped Dose-Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol.

Authors: Ruth Gallily, Zhannah Yekhtin, Lumír Ondřej Hanuš
Pharmacology & Pharmacy, 2015

Cannabidiol (CBD), a major constituent of Cannabis, has been shown to be a powerful anti-in- flammatory and anti-anxiety drug, without exerting a psychotropic effect. However, when given either intraperitoneally or orally as a purified product, a bell-shaped dose-response was…

Successful authorised therapy of treatment resistant adult ADHD with Cannabis: experience from a medical practice with 30 patients

Authors: Eva Milz, Franjo Grotenhermen
Conference Poster, 2015

The medical certificates of 30 patients with adult ADHD, who were granted approval by the German Health Ministry to use cannabis flowers between 2012 and 2014, were analysed with regard to course of disease, previous treatment efforts, and effects of self-medi…