The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities.

Authors: Tamás Bíró, Balázs I. Tóth, György Haskó, Ralf Paus, Pál Pacher
Trends in Pharmacological Sciences, August 2009

The newly discovered endocannabinoid system (ECS; comprising the endogenous lipid mediators endocannabinoids present in virtually all tissues, their G-protein-coupled cannabinoid receptors, biosynthetic pathways and metabolizing enzymes) has been implicated in multiple regulat…