Interplay between endocannabinoids, steroids and cytokines in the control of human reproduction.

Authors: Natalia Battista, N. Pasquariello, M. Di Tommaso, Mauro Maccarrone
Journal of Neuroendocrinology, May 2008

The use of marijuana, which today is the most used recreational drug, has been demonstrated to affect adversely reproduction. Marijuana smokers, both men and women, show impaired fertility, owing to defective signalling pathways, aberrant hormonal regulation, or wrong timing d…

Multiple roles for the endocannabinoid system during the earliest stages of life: pre- and postnatal development.

Authors: Ester Fride
Journal of Neuroendocrinology, May 2008

The endocannabinoid system, including its receptors (CB(1) and CB(2)), endogenous ligands (‘endocannabinoids’), synthesising and degrading enzymes, as well as transporter molecules, has been detected from the earliest stages of embryonic development and throughout pre- and pos…