The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.

Authors: Luciano De Petrocellis, Dominique Melck, Antonella Palmisano, Tiziana Bisogno, et al
PNAS, 7 July 1998

Anandamide was the first brain metabolite shown to act as a ligand of “central” CB1 cannabinoid receptors. Here we report that the endogenous cannabinoid potently and selectively inhibits the proliferation of human breast cancer cells in vitro. Anandamide dose-dependently inhi…