Pharmacokinetics of delta9-tetrahydrocannabinol in dogs.

Authors: Edward R. Garrett, Edward R. Garrett, C. Anthony Hunt
Journal of Pharmaceutical Sciences, March 1977

The pharmacokinetics of intravenously administered 14C-delta9-tetrahydrocannabinol and derived radiolabeled metabolites were studied in three dogs at two doses each at 0.1 or 0.5 and 2.0 mg/kg. Two dogs were biliary cannulated; total bile was collected in one and sampled in th…