THC and COX2 Mediation

By | Research Articles, THC

THC and COX2 Mediation | Ibuprofen THC | NSAIDS THC

This study, from Louisiana State University and published in the journal Cell in November, 2013 showed that unwanted side effects of THC-Rich cannabis could be eliminated or reduced while retaining its beneficial effects by administering a COX-2 inhibitor or NSAID along with THC. Read More

The Role of Cannabinoids in Prostate Cancer

By | Cancer, CBD, Research Articles, THC

The Role of Cannabinoids in Prostate Cancer

From the Indian Journal of Urology in 2012 comes this information regarding cannabis and prostate cancer: ‘It is our conclusion that it would be of interest to conduct clinical trials involving medicinal cannabis or other cannabinoid agonists, comparing clinical markers such as PSA with controls, especially in men with bone metastatic prostate cancer, whom would not only benefit from the possible anti-androgenic effects of cannabinoids but also from analgesia of bone pain, improving quality of life, while reducing narcotic consumption and preventing opioid dependence.’ Read More

Opposite Effects of D-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology

By | CBD, Research Articles, THC

THC and CBD have Opposite Effects on Brain and Body

Can CBD counteract adverse effects of excessive THC? In this 2010 issue of the journal Neuropsychopharmacology, they showed that pretreatment with CBD prevented the acute induction of psychotic symptoms by D-9-tetrahydrocannabinol. D-9-THC and CBD can have opposite effects on regional brain function, which may underlie their different symptomatic and behavioral effects, and CBD’s ability to block the psychotogenic effects of D-9-THC. Read More

The Endocannabinoid System and Memory Disorders

By | Brain Health, Research Articles, THC

THC and Memory: The most recent Journal of Cognitive Neuroscience reports on a study out of the University Medical Center in Utrecht, the Netherlands. Deficits in memory function are an incapacitating aspect of various psychiatric and neurological disorders. Animal studies have recently provided strong evidence for involvement of the endocannabinoid (eCB) system in memory function. The Abstract is posted here. Read More