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Brain Health

Cannabidiol Inhibits Human Glioma Cell Migration

By | Brain Health, Cancer, CBD, Research Articles

CaCannabidiol Inhibits Human Glioma Cell MigrationIn 2005, the British Journal of Pharmacology published a study evaluating the ability of cannabidiol (CBD) to impair the migration of tumor cells and thus act as a potential antitumoral compound. The results of the study reinforce the evidence of antitumoral properties of CBD, demonstrating its ability to limit tumor invasion, although the mechanism of its pharmacological effects remains to be clarified. This antimigratory property, together with the known antiproliferative and apoptotic features of CBD, strengthen the evidence for its use as a potential antitumoral agent.
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Effects of Long Term Cannabis Use

By | Behavioral Health, Brain Health, Research Articles

Effects Of Long Term Cannabis Use

In a 2003 issue of the Journal of International Neuropsychological Society is this study looking at the possible long-term residual effects of using cannabis. The results of this meta-analytic study failed to reveal a substantial, systematic effect of long-term, regular cannabis consumption on the neurocognitive functioning of users who were not acutely intoxicated. Read More

Intratumor THC For Glioblastoma Multiforme

By | Brain Health, Cancer, Research Articles, THC

Intratumor THC For Glioblastoma Multiforme

Published in the British Journal of Cancer in 2006, these scientists reported ‘the first clinical study aimed at assessing cannabinoid antitumoral action, specifically a pilot phase I trial in which nine patients with recurrent glioblastoma multiforme were administered THC intratumoraly. The patients had previously failed standard therapy (surgery and radiotherapy) and had clear evidence of tumour progression’. Read More

Cannabidiol Inhibits Proliferation and Invasion in Glioma Cells

By | Brain Health, Cancer, CBD, Research Articles

Cannabidiol Inhibits Proliferation and Invasion in Glioma Cells | CBD Brain Cancer

This study out of Spain and published in October 2013, confirms the antiproliferative and antiinvasive effects of CBD in two different glioma cell lines. Interestingly, these effects can also be extended to glioma cells that are well known to be D9-THC-resistant. This data adds further insights into CBD antitumor action, showing its ability to influence multiple cellular targets in the two cell lines with partial overlap. Read More

Endocannabinoid System Removes Damaged Brain Cells, Improves Mitochondrial Health

By | Brain Health, Endocannabinoid System, Research Articles

Endocannabinoid System Removes Damaged Cells, Improves Mitochondrial Health

This December 2012 review, published in Philosophical Transactions of the Royal Society B out of Germany, suggests that activating the brain’s cannabinoid system may trigger a sort of anti-oxidant cleanse, removing damaged cells and improving the efficiency of the mitochrondria, the energy source that powers cells, ultimately leading to a more robustly functioning brain. Read More

Brain Tumors Regressing — Thanks to Cannabis?

By | Brain Health, Cancer, Research Articles

Cannabis for Brain Tumors | Effect of Cannabis on Gliomas

Cannabis for Brain Tumors: Two case reports in the journal Children’s Nervous System by Mansoor Foroughi and colleagues at BC Children’s Hospital in Vancouver discuss the “possible role of Cannabis inhalation” in the spontaneous regression of brain tumors (pilocytic astrocytomas). The cases involve a girl who underwent surgery at age 11 and a girl who underwent surgery at 13. In each case a remnant of the tumor could not be removed. Read More