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Brain Injuries

Cannabinoids: well-suited candidates for the treatment of perinatal brain injury.

By | Brain Injuries, Nervous System Diseases, Research Articles

Authors: David Fernández-López, Ignacio Lizasoain, Maria Ángeles Moro, José Martínez-Orgado
Brain Sciences, 10 July 2013

Perinatal brain injury can be induced by a number of different damaging events occurring during or shortly after birth, including neonatal asphyxia, neonatal hypoxia-ischemia and stroke-induced focal ischemia. Typical manifestations of these conditions are the presence of glut…

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Cannabinoids and brain injury: therapeutic implications.

By | Brain Injuries, Nervous System Diseases, Pain

Authors: Raphael Mechoulam, David Panikashvili, Esther Shohami
Trends in Molecular Medicine, February 2002

Mounting in vitro and in vivo data suggest that the endocannabinoids anandamide and 2-arachidonoyl glycerol, as well as some plant and synthetic cannabinoids, have neuroprotective effects following brain injury. Cannabinoid receptor agonists inhibit glutamatergic synaptic tran…

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