Category

Muscular Diseases

The influence of THC:CBD oromucosal spray on driving ability in patients with multiple sclerosis-related spasticity.

By | Driving, Immune System Diseases , Multiple Sclerosis, Muscle Spasticity, Muscular Diseases

Authors: Elisabeth G. Celius, Carlos Vila
Brain and Behavior, 6 April 2018

BACKGROUND: Driving ability is a key function for the majority of patients with multiple sclerosis (MS) to help maintain daily interactions. Both physical and cognitive disability, as well as treatments, may affect the ability to drive. Spasticity is a common symptom associate…

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Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review.

By | Immune System Diseases , Medical Cannabis, Multiple Sclerosis, Muscle Spasticity, Muscular Diseases, Nervous System Diseases, Neuromuscular Diseases, Pain

Authors: Kevin P. Hill
JAMA, 23 June 2015

IMPORTANCE: As of March 2015, 23 states and the District of Columbia had medical marijuana laws in place. Physicians should know both the scientific rationale and the practical implications for medical marijuana laws. OBJECTIVE: To review the pharmacology, indications, and law…

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Cannabinoids for Medical Use: A Systematic Review and Meta-analysis.

By | Anorexia, Behavioral Health, Eye Diseases, Feeding and Eating Disorders, Glaucoma, Medical Cannabis, Muscle Spasticity, Muscular Diseases, Pain, Tourette Syndrome

Authors: Penny F. Whiting, Robert F. Wolff, Sohan Deshpande, Marcello Di Nisio, Steven Duffy, et al
JAMA, 23 June 2015

IMPORTANCE: Cannabis and cannabinoid drugs are widely used to treat disease or alleviate symptoms, but their efficacy for specific indications is not clear. OBJECTIVE: To conduct a systematic review of the benefits and adverse events (AEs) of cannabinoids. DATA SOURCES: Twenty…

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Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial.

By | Immune System Diseases , Multiple Sclerosis, Muscle Spasticity, Muscular Diseases, Pain

Authors: Jody Corey-Bloom, Tanya Wolfson, Anthony Gamst, Shelia Jin, Thomas D. Marcotte, et al
CMAJ, 10 July 2012

BACKGROUND: Spasticity is a common and poorly controlled symptom of multiple sclerosis. Our objective was to determine the short-term effect of smoked cannabis on this symptom. METHODS: We conducted a placebo-controlled, crossover trial involving adult patients with multiple s…

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Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

By | Brain Disorders, Digestive System Diseases, General Information, Headache Disorders, Irritable Bowel Syndrome, Medical Cannabis, Muscular Diseases, Nervous System Diseases

Authors: Ethan Budd Russo
Neuroendocrinology Letters, April 2008

OBJECTIVES: This study examines the concept of clinical endocannabinoid deficiency (CECD), and the prospect that it could underlie the pathophysiology of migraine, fibromyalgia, irritable bowel syndrome, and other functional conditions alleviated by clinical cannabis. METHODS:…

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Chronic Cannabis Use in the Compassionate Investigational New Drug Program

By | Eye Diseases, Glaucoma, Immune System Diseases , Multiple Sclerosis, Muscle Spasticity, Muscular Diseases, Pain

Authors: Ethan Russo, Mary Lynn Mathre, Al Byrne, Robert Velin, Paul J. Bach, Juan Sanchez-Ramos, et al
Journal of Cannabis Therapeutics, 2002

The Missoula Chronic Clinical Cannabis Use Study was proposed to investigate the therapeutic bepnefits and adverse effects of prolonged use of “medical marijuana” in a cohort of seriously ill patients. Use of cannabis was approved through the Compassionate Inves-tigational New…

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