Category

Substance-Related Disorders

Cocaine and Marijuana Use Among Young Adults With Myocardial Infarction.

By | Behavioral Health, Cardiovascular Diseases, Substance-Related Disorders

Authors: Ersilia M. DeFilippis, Avinainder Singh, Sanjay Divakaran, Ankur Gupta, Bradley L. Collins, et al
Journal of the American College of Cardiology, 5 June 2018

BACKGROUND: Substance abuse is increasingly prevalent among young adults, but data on cardiovascular outcomes remain limited. OBJECTIVES: The objectives of this study were to assess the prevalence of cocaine and marijuana use in adults with their first myocardial infarction (M…

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The effects of Δ9-tetrahydrocannabinol on the dopamine system.

By | Behavioral Health, Substance-Related Disorders

Authors: Michael A. P. Bloomfield, Abhishekh H. Ashok, Nora D. Volkow, Oliver D. Howes
Nature, 17 November 2016

The effects of Δ9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, are a pressing concern for global mental health. Patterns of cannabis use are changing drastically owing to legalization, the availability of synthetic analogues (commonly termed spice)…

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Does Cannabis Cause, Exacerbate or Ameliorate Psychiatric Disorders? An Oversimplified Debate Discussed.

By | Behavioral Health, Substance-Related Disorders

Authors: Margaret Haney, A. Eden Evins
Neuropsychopharmacology, January 2016

There have been extensive policy shifts in the legality of recreational and therapeutic use of cannabis in the United States, as well as a steady increase in the number of people using the drug on a regular basis. Given these rapid societal changes, defining what is known scie…

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Psychotic experiences are linked to cannabis use in adolescents in the community because of common underlying environmental risk factors.

By | Adolescent, Behavioral Health, Substance-Related Disorders

Authors: Sania Shakoor, Helena M.S. Zavos, Philip McGuire, Alastair G. Cardno, et al
Psychiatry Research, 30 June 2015

Cannabis users are more likely to have psychotic experiences (PEs). The degree to which these associations are driven by genetic or environmental influences in adolescence is unknown. This study estimated the genetic and environmental contributions to the relationship between…

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Use of Prescription Pain Medications Among Medical Cannabis Patients

By | Behavioral Health, Medical Cannabis, Pain, Substance-Related Disorders

Authors: Brian E. Perron, Kipling Bohnert, Angela K. Perone, Marcel O. Bonn-Miller, Mark Ilgen
Journal of Studies on Alcohol and Drugs, May 2015

OBJECTIVE: Management of chronic pain is one of the most common reasons given by individuals seeking medical cannabis. However, very little information exists about the concurrent use of cannabis and prescription pain medication (PPM). This study fills this gap in knowledge by…

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Young adult sequelae of adolescent cannabis use: an integrative analysis.

By | Adolescent, Behavioral Health, Substance-Related Disorders

Authors: Edmund Silins, L. John Horwood, George C. Patton, David M. Fergusson, Craig A. Olsson, et al
The Lancet Psychiatry, September 2014

BACKGROUND: Debate continues about the consequences of adolescent cannabis use. Existing data are limited in statistical power to examine rarer outcomes and less common, heavier patterns of cannabis use than those already investigated; furthermore, evidence has a piecemeal app…

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Medical cannabis laws and opioid analgesic overdose mortality in the United States, 1999-2010.

By | Addiction, Opioids, Substance-Related Disorders

Authors: Marcus A. Bachhuber, Brendan Saloner, Chinazo O. Cunningham, et al
JAMA Internal Medicine, October 2014

IMPORTANCE: Opioid analgesic overdose mortality continues to rise in the United States, driven by increases in prescribing for chronic pain. Because chronic pain is a major indication for medical cannabis, laws that establish access to medical cannabis may change overdose mort…

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Intermittent marijuana use is associated with improved retention in naltrexone treatment for opiate-dependence.

By | Addiction, Behavioral Health, Opioids, Substance-Related Disorders

Authors: Wilfrid Noel Raby, Kenneth M. Carpenter, Jami Rothenberg, Adam C. Brooks, Huiping Jiang, et al
American Journal on Addictions, July/August 2009

Naltrexone is a theoretically promising alternative to agonist substitution treatment for opioid dependence, but its effectiveness has been severely limited by poor adherence. This study examined, in an independent sample, a previously observed association between moderate can…

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Does using marijuana increase the risk for developing schizophrenia?

By | Behavioral Health, Schizophrenia Spectrum, Substance-Related Disorders

Authors: A. Eden Evins, Alan I. Green, John M. Kane, Sir Robin M. Murray
The Journal of Clinical Psychiatry, April 2013

As more US states and other countries consider legalizing marijuana, clinicians need to know the possible effects of this drug. Research has shown a connection between marijuana use and an increased risk for schizophrenia in young people who are vulnerable to developing psycho…

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Prescribing cannabis for harm reduction.

By | Behavior & Behavior Mechanisms, Harm Reduction, Opioids, Pain, Substance-Related Disorders

Authors: Mark Collen
Harm Reduction Journal, 1 January 2012

Neuropathic pain affects between 5% and 10% of the US population and can be refractory to treatment. Opioids may be recommended as a second-line pharmacotherapy but have risks including overdose and death. Cannabis has been shown to be effective for treating nerve pain without…

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