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Stress Disorders – Post-Traumatic

Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes.

By | Anorexia, Behavioral Health, Brain Disorders, Clinical Endocannabinoid Deficiency, Digestive System Diseases, Headache Disorders, Immune System Diseases , Irritable Bowel Syndrome, Multiple Sclerosis, Nervous System Diseases, Parkinsonian Disorders, Stress Disorders - Post-Traumatic

Authors: Ethan B. Russo
Cannabis and Cannabinoid Research, 1 July 2016

Medicine continues to struggle in its approaches to numerous common subjective pain syndromes that lack objective signs and remain treatment resistant. Foremost among these are migraine, fibromyalgia, and irritable bowel syndrome, disorders that may overlap in their affected p…

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Use and effects of cannabinoids in military veterans with posttraumatic stress disorder.

By | Behavioral Health, Stress Disorders - Post-Traumatic

Authors: Kevin Betthauser, Jeffrey Pilz, Laura E. Vollmer
American Journal of Health-System Pharmacy, 1 August 2015

PURPOSE: Published evidence regarding the use of cannabis and cannabis derivatives by military veterans with posttraumatic stress disorder (PTSD) is reviewed. SUMMARY: When inhaled or delivered orally or transdermally, cannabinoids (the psychoactive components of unrefined mar…

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PTSD symptom reports of patients evaluated for the New Mexico Medical Cannabis Program.

By | Behavioral Health, Medical Cannabis, Stress Disorders - Post-Traumatic

Authors: George R. Greer, Charles S. Grob, Adam L. Halberstadt
Journal of Psychoactive Drugs, January-March 2014

BACKGROUND: New Mexico was the first state to list post-traumatic stress disorder (PTSD) as a condition for the use of medical cannabis. There are no published studies, other than case reports, of the effects of cannabis on PTSD symptoms. The purpose of the study was to report…

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Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study.

By | Behavioral Health, Stress Disorders - Post-Traumatic

Authors: A Neumeister, M D Normandin, R H Pietrzak, D Piomelli, M Q Zheng, A Gujarro-Anton, et al
Molecular Psychiatry, September 2013

Endocannabinoids and their attending cannabinoid type 1 (CB1) receptor have been implicated in animal models of post-traumatic stress disorder (PTSD). However, their specific role has not been studied in people with PTSD. Herein, we present an in vivo imaging study using posit…

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The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD).

By | Anxiety, Behavior & Behavior Mechanisms, Behavioral Health, Stress Disorders - Post-Traumatic

Authors: Viviana Trezza, Patrizia Campolongo
Frontiers in Behavioral Neuroscience, 9 August 2013

Post-traumatic stress disorder (PTSD) is a psychiatric disorder of significant prevalence and morbidity, whose pathogenesis relies on paradoxical changes of emotional memory processing. An ideal treatment would be a drug able to block the pathological over-consolidation and co…

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Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence.

By | Anxiety, Behavior & Behavior Mechanisms, Behavioral Health, Stress Disorders - Post-Traumatic

Authors: Torsten Passie, Hinderk M. Emrich, Matthias Karst, Simon D. Brandt, John H. Halpern
Drug Testing and Analysis, July-August 2012

It is known from clinical studies that some patients attempt to cope with the symptoms of post-traumatic stress disorder (PTSD) by using recreational drugs. This review presents a case report of a 19-year-old male patient with a spectrum of severe PTSD symptoms, such as intens…

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Posttraumatic Stress Symptom Severity and Marijuana Use Coping Motives: A Test of the Mediating Role of Non-Judgmental Acceptance within a Trauma-Exposed Community Sample.

By | Behavioral Health, Stress Disorders - Post-Traumatic

Authors:

Marcel O. Bonn-Miller, Anka A. Vujanovic, Michael P. Twohig, Johnna L. Medina, Jennifer L. Huggins


Published in Mindfulness

25 May 2010

 

Abstract

We examined the role of non-judgmental acceptance in the relation between posttraumatic stress symptom severity and marijuana use coping motives. These relations were examined among 97 (46 women) adults (M age = 21.57 years, SD = 6.32) who met DSM-IV-defined PTSD Criterion A for at least one traumatic event exposure and reported using marijuana in the past 30 days. Consistent with expectation, greater levels of posttraumatic stress symptom severity were associated with greater levels of coping-oriented marijuana use motives, as well as lower levels of non-judgmental acceptance. Furthermore, non-judgmental acceptance was inversely associated with coping-oriented marijuana use motives. Finally, non-judgmental acceptance was found to partially mediate the association between posttraumatic stress symptom severity and marijuana use coping motives. Results are discussed in terms of better understanding the role of non-judgmental acceptance in coping-oriented marijuana use among trauma-exposed populations.

 

DOI: 10.1007/s12671-010-0013-6

PAYWALL

Citation:

Bonn-Miller MO, Vujanovic AA, Twohig MP, Medina JL, Huggins JL. Posttraumatic Stress Symptom Severity and Marijuana Use Coping Motives: A Test of the Mediating Role of Non-Judgmental Acceptance within a Trauma-Exposed Community Sample. Mindfulness (N Y). 2010;1(2):98-106. doi:10.1007/s12671-010-0013-6

The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD).

By | Behavioral Health, Stress Disorders - Post-Traumatic

Authors: George A. Fraser
CNS Neuroscience & Therapeutics, Winter 2009

This is the report of an open label clinical trial to evaluate the effects of nabilone, an endocannabinoid receptor agonist, on treatment-resistant nightmares in patients diagnosed with posttraumatic stress disorder (PTSD). METHODS: Charts of 47 patients diagnosed with PTSD an…

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Association of the cannabinoid receptor gene (CNR1) with ADHD and post‐traumatic stress disorder.

By | Attention Deficit & Disruptive Behavior Disorders, Stress Disorders - Post-Traumatic

Authors: Ake T. Lu, Matthew N. Ogdie, Marjo‐Ritta Järvelin, Irma K. Moilanen, Sandra K. Loo, et al
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 22 January 2008

Attention deficit hyperactivity disorder (ADHD) is a highly heritable disorder affecting some 5-10% of children and 4-5% of adults. The cannabinoid receptor gene (CNR1) is a positional candidate gene due to its location near an identified ADHD linkage peak on chromosome 6, its…

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