Category

Schizophrenia Spectrum

Proportion of patients in south London with first-episode psychosis attributable to use of high potency cannabis: a case-control study.

By | Behavioral Health, Schizophrenia Spectrum

Authors: Marta Di Forti, Arianna Marconi, Elena Carra, Sara Fraietta, Antonella Trotta, Matteo Bonomo, et al
The Lancet Psychiatry, March 2015

BACKGROUND: The risk of individuals having adverse effects from drug use (eg, alcohol) generally depends on the frequency of use and potency of the drug used. We aimed to investigate how frequent use of skunk-like (high-potency) cannabis in south London affected the associatio…

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Does using marijuana increase the risk for developing schizophrenia?

By | Behavioral Health, Schizophrenia Spectrum, Substance-Related Disorders

Authors: A. Eden Evins, Alan I. Green, John M. Kane, Sir Robin M. Murray
The Journal of Clinical Psychiatry, April 2013

As more US states and other countries consider legalizing marijuana, clinicians need to know the possible effects of this drug. Research has shown a connection between marijuana use and an increased risk for schizophrenia in young people who are vulnerable to developing psycho…

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Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia.

By | Behavioral Health, Schizophrenia Spectrum

Authors: F. M. Leweke, D. Piomelli, F. Pahlisch, D. Muhl, C. W. Gerth, C. Hoyer, J. Klosterkötter, et al
Translational Psychiatry, 20 March 2012

Cannabidiol is a component of marijuana that does not activate cannabinoid receptors, but moderately inhibits the degradation of the endocannabinoid anandamide. We previously reported that an elevation of anandamide levels in cerebrospinal fluid inversely correlated to psychot…

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Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action.

By | Anxiety Disorders, Behavioral Health, Nervous System Diseases, Parkinsonian Disorders, Schizophrenia Spectrum

Authors: Antonio Waldo Zuardi
Brazilian Journal of Psychiatry, September 2008

OBJECTIVE: The aim of this review is to describe the historical development of research on cannabidiol. METHOD: This review was carried out on reports drawn from Medline, Web of Science and SciELO. DISCUSSION: After the elucidation of the chemical structure of cannabidiol in 1…

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