Category

Anxiety

Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation.

By | Anxiety, Behavior & Behavior Mechanisms

Authors: R J Bluett, J C Gamble-George, D J Hermanson, N D Hartley, L J Marnett, S Patel
Translational Psychiatry, 8 July 2014

Stress is a major risk factor for the development of mood and anxiety disorders; elucidation of novel approaches to mitigate the deleterious effects of stress could have broad clinical applications. Pharmacological augmentation of central endogenous cannabinoid (eCB) signaling…

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Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects.

By | Anxiety, Behavior & Behavior Mechanisms

Authors: A. W. Zuardi, I. Shirakawa, E. Finkelfarb, I. G. Karniol
Psychopharmacology, DATE

The object of the experiment was to verify whether cannabidiol (CBD) reduces the anxiety provoked by delta 9-THC in normal volunteers, and whether this effect occurs by a general block of the action of delta 9-THC or by a specific anxiolytic effect. Appropriate measurements an…

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