Category

THC

Synthetic and Natural Cannabinoids: the Cardiovascular Risk

By | Cardiovascular, Heart Health, Research Articles, THC

Synthetic and Natural Cannabinoids: the Cardiovascular RiskFrom The British Journal of Cardiology, this 2015 editorial, by neurologist and cannabis research pioneer Dr. Ethan Russo, explores the cardiovascular risks associated with cannabis, suggesting that ultra-low THC and therapeutic phytocannabinoid dosing are cardio protective, while high doses of THC and high levels of stimulation of the CB1 receptor pose cardiovascular risks. Read More

THC Reduces Human Breast Cancer Cell Proliferation

By | Breast Cancer, Cancer, Research Articles, THC
THC Reduces Human Breast Cancer Cell Proliferation THC and breast cancer – Little is known about the effect of cannabinoids on the cell cycle, the main process controlling cell fate. This study out of Spain, published in a 2006 issue of Cancer Research, shows that Δ9-tetrahydrocannabinol (THC), through activation of CB2 cannabinoid receptors, reduces human breast cancer cell proliferation by blocking the progression of the cell cycle and by inducing apoptosis

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Medical Cannabis Strain Content Satisfaction

By | CBD, Research Articles, THC, THCV

Medical Cannabis Strain Content Satisfaction

This study, published in the June 2014 issue of the Journal of Clinical Psychopharmacology, describes more than 100 patients reporting about the therapeutic satisfaction with their pharmaceutical-grade cannabis product. Furthermore, differences in subjective effects among the available strains are investigated. Read More

Intratumor THC For Glioblastoma Multiforme

By | Brain Health, Cancer, Research Articles, THC

Intratumor THC For Glioblastoma Multiforme

Published in the British Journal of Cancer in 2006, these scientists reported ‘the first clinical study aimed at assessing cannabinoid antitumoral action, specifically a pilot phase I trial in which nine patients with recurrent glioblastoma multiforme were administered THC intratumoraly. The patients had previously failed standard therapy (surgery and radiotherapy) and had clear evidence of tumour progression’. Read More

Crohn’s Disease & THC

By | Crohn's Disease, Research Articles, THC

Crohn's Disease & THC | Cannabis Research | THC Research

A 2013 study Published in the journal Pharmacology involved 21 patients with Crohn’s disease unresponsive to standard IBD treatment. The study was able to demonstrate that an 8-week treatment with tetrahydrocannabinol (THC)-rich cannabis caused a decrease in the Crohn’s disease activity index in 90% of patients without producing significant side effects. Read More

THC & Exercise Performance

By | Endocannabinoid System, Research Articles, THC

THC And Exercise Performance | THC Research

In a 2013 issue of the journal Nutrition & Metabolism, four drugs (ethanol, caffeine, nicotine & THC) were evaluated for their effect on exercise metabolism. Overall, it appears that cannabis does not have ergogenic potential in sports activities and thus, its inclusion on the banned list is likely a function of its illicitness. Read More

Cannabinoid Receptor Pharmacology

By | CBD, Endocannabinoid System, Research Articles, THC, THCV

Cannabinoid Receptor Pharmacology | Cannabinoid Receptor Agonists

Cannabis sativa is the source of a unique set of compounds known collectively as plant cannabinoids or phytocannabinoids. This review published in 2008 in the Journal of British Pharmacology focuses on the manner with which three of these compounds, (_)-trans-D9-tetrahydrocannabinol (D9-THC), (_)-cannabidiol (CBD) and (_)-trans-D9-tetrahydrocannabivarin (D9-THCV), interact with cannabinoid receptors CB1 and CB2. Read More

MS Spasticity, THC:CBD Cannabis Spray, And Driving

By | CBD, Driving, Multiple Sclerosis, Research Articles, THC

MS Spasticity, THC:CBD Cannabis Spray, And Driving | Cannabis and Multiple Sclerosis

Cannabis and Multiple Sclerosis: Is driving safe for MS patients who use cannabis for resistant spasticity? In this poster presentation by German neurologists they show that THC:CBD oromucosal spray (Sativex), when used for 4-6 weeks by patients with multiple sclerosis, did not harm driving skills. As a matter of fact, there was significant improvement in a motor reaction task test. Read More